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KMID : 0387820140210020172
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Clinical Pediatric Hematology-Oncology
2014 Volume.21 No. 2 p.172 ~ p.176
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A Case of Appendicitis with Liver Abscesses Developed during Allogeneic Hematopoietic Stem Cell Transplantation
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Lee Seul-Bee
Lee Jung-Min
Lee Sun-Wha
Yoo Eun-Sun
Ryu Kyung-Ha
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Abstract
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A 10-year-old boy with severe aplastic anemia was admitted for allogeneic hematopoietic stem cell transplantation. After conditioning chemotherapy using cyclophosphamide, flu-darabine, and antithymocyte immunoglobulin, he presented with fever and abdominal pain on day 0 of stem cell transplantation. After diagnosis of acute appendicitis with minor perforation, appendectomy was performed just after cell infusion. A week after the procedure, he showed two huge liver abscesses in S4 and S6 segments. We used broad spectrum antibiotics along with antifungal agents. Percutaneous drainage was at-tempted, but no fluid was removed and no microorganisms were isolated. After 7 weeks of antibiotics and antifungal therapy, liver abscesses showed improvement. We report a case of successfully treated appendicitis with liver abscesses in a severely neutropenic patient during allogeneic hematopoietic stem cell transplantation.
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KEYWORD
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Allogneic hematopoietic stem cell transplantation, Appendicitis, Neutropenic patients, Liver abscess, Typhlitis
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